Bromhexina

Also known as N-Cyclohexyl-N-methyl-(2-amino-3,5-dibrombenzyl)amine, Tauglicolo, Fluibron, Bromexina, Bromhexinum, 3,5-Dibromo-N(alpha)-cyclohexyl-N(alpha)-methyltoluene-alpha-2-diamine, Bromhexine

medicamento usado como expectorante y mucolítico

In the Vinony graph

Vinony's link graph records 98 inbound references to Bromhexina, and connects out to antitussive, mucokinetic and liver.

It sits within the topics Anilines, Antidotes and Bromobenzene derivatives.

Vinony links it to 26 Wikipedia language editions.

Chemical data

Formula: C14H20Br2N2
Molecular weight: 376.13 g/mol
IUPAC name: 2,4-dibromo-6-[[cyclohexyl(methyl)amino]methyl]aniline
SMILES: CN(CC1=C(C(=CC(=C1)Br)Br)N)C2CCCCC2
InChIKey: OJGDCBLYJGHCIH-UHFFFAOYSA-N
XLogP: 4.3
Polar surface area: 29.3 Å²
H-bond donors: 1
H-bond acceptors: 2
Formal charge: 0

via PubChem

Drug data · ChEMBL

Max clinical phase: Approved
Molecule type: Small molecule
Indications: malaria, COVID-19

via ChEMBL · EBI

Research

1,366 papers

Bromhexine.Indian pediatrics · 1990
Beyond the lungs: Exploring diverse applications of bromhexine and ambroxol.Life sciences · 2024
Enhancement of lung levels of antibiotics by ambroxol and bromhexine.Expert opinion on drug metabolism & toxicology · 2019
[Bromhexine].Deutsche medizinische Wochenschrift (1946) · 1979
[Bromhexine (Bisolvon). An evaluation from the literature].Ugeskrift for laeger · 1974

via PubMed

Wikidata facts

Subclass of: chemical compound
Has part: bromine
Mass: 373.99932284000005
Has use: medication

Show 8 more facts

canonical SMILES: CN(CC1=CC(=CC(=C1N)Br)Br)C2CCCCC2
chemical formula: C₁₄H₂₀Br₂N₂
subject has role: mucokinetic
World Health Organisation international non-proprietary name: bromhexine
medical condition treated: cough
Commons category: Bromhexine
found in taxon: Justicia adhatoda
defined daily dose: 24

Sources (3)

via Wikidata · CC0

Article · Español

La Bromhexina (bromhexina clorhidrato) es un agente mucolítico y expectorante utilizado en el tratamiento de trastornos respiratorios asociados con mucosidad viscosa y excesiva.

Abstract from DBpedia / Wikipedia · CC BY-SA