CD82 molecule

Also known as CD82 antigen, kangai 1 (suppression of tumorigenicity 6, prostate; CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal and antibody IA4)), tetraspanin-27, CD82, Suppressor of tumorigenicity 6 protein, inducible membrane protein R2, metastasis suppressor Kangai-1, C33 antigen

mammalian protein found in Homo sapiens

In the Vinony graph

Within Vinony's link graph, CD82 molecule is referenced by 419 other articles, and connects out to PubMed, Ensembl genome database project and CD1.

Vinony files it under Clusters of differentiation, Genes on human chromosome 11 and Long stubs with short prose.

Its subject is documented across 7 Wikipedia language editions.

Protein · UniProt

CD82 antigen

Gene: CD82
Organism: Homo sapiens (Human)
Length: 267 aa
Molecular mass: 29,626 Da
Evidence: 1: Evidence at protein level

Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling (PubMed:19497983). Participates thereby in diverse biological functions such as cell signal transduction, adhesion, migration and protein trafficking. Acts as a attenuator of EGF signaling, facilitating ligand-induced endocytosis of the receptor and its subsequent desensitization (PubMed:10985391, PubMed:35538033). Mechanistically, modulates ligand-induced ubiquitination and trafficking of EGFR via E3 ligase CBL phosphoryl…

3D-structureAlternative splicingCell membraneCytoplasmic vesicleGlycoproteinLipoproteinMembranePalmitate

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Swiss-Prot (reviewed) · via UniProt