CDSN
Sign in to saveAlso known as D6S586E, HTSS, HTSS1, HYPT2, PSS, PSS1, corneodesmosin, S
Corneodesmosin is a protein that in humans is encoded by the CDSN gene.
Gene data
CDSN- Name
- corneodesmosin
- Type
- protein-coding
- Chromosome
- HSCHR6_MHC_QBL_CTG1
- Position
- 2,373,089–2,378,448 (−)
- Aliases
- HTSS, HTSS1, HYPT2, PSS, PSS1
- Ensembl
- ENSG00000237123
- RefSeq RNA
- NM_001264.5
- RefSeq protein
- NP_001255.4
This gene encodes a protein found in corneodesmosomes, which localize to human epidermis and other cornified squamous epithelia. The encoded protein undergoes a series of cleavages during corneocyte maturation. This gene is highly polymorphic in human populations, and variation has been associated with skin diseases such as psoriasis, hypotrichosis and peeling skin syndrome. The gene is located in the major histocompatibility complex (MHC) class I region on chromosome 6. [provided by RefSeq, Dec 2014].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 48005
- exact match
- identifiers.org/ncbigene/1041
- genomic start
- 31115087
- genomic end
- 31088223
- cytogenetic location
- 6p21.33
Sources (4)
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Article
3 sectionsContents
- See also
- References
- Further reading
Corneodesmosin is a protein that in humans is encoded by the CDSN gene.
This gene encodes a protein found in corneodesmosomes, which localize to the human epidermis and other cornified squamous epithelia. During maturation of the cornified layers, the protein undergoes a series of cleavages, which are thought to be required for desquamation. The gene is located in the major histocompatibility complex (MHC) class I region on chromosome 6.