CD248

Also known as CD164L1, TEM1, CD248 molecule

Endosialin is a protein that in humans is encoded by the CD248 gene.

In the Vinony graph

Within Vinony's link graph, CD248 is referenced by 361 other articles, and connects out to PubMed, Ensembl genome database project and CD1.

Vinony files it under Clusters of differentiation and Genes on human chromosome 11.

Its subject is documented across 7 Wikipedia language editions.

Gene data

CD248

Name: CD248 molecule
Type: protein-coding
Position: 66,314,494–66,317,044 (−)
Aliases: CD164L1, TEM1
Ensembl: ENSG00000174807
RefSeq RNA: NM_020404.3
RefSeq protein: NP_065137.1

Predicted to enable extracellular matrix binding activity and extracellular matrix protein binding activity. Predicted to be involved in cell migration. Predicted to act upstream of or within several processes, including anatomical structure regression; lymph node development; and positive regulation of endothelial cell apoptotic process. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]

Gene Ontology

Biological process

cell migration

Molecular function

calcium ion binding protein binding extracellular matrix binding extracellular matrix binding extracellular matrix protein binding

Cellular component

cytoplasm external side of plasma membrane membrane extracellular matrix extracellular exosome

via MyGene.info

Gene · Ensembl

CD248 molecule

Symbol: CD248
Biotype: Protein coding
Organism: Homo sapiens
Location: 11:66,314,494-66,317,044
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

Show 7 more facts

HomoloGene ID: 10699
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/57124
genomic end: 66084515
genomic start: 66314494
chromosome: human chromosome 11
cytogenetic location: 11q13.2

Sources (3)

via Wikidata · CC0

~1 min read

Encyclopedic overview

4 sections

Contents

See also
References
Further reading
External links

Endosialin is a protein that in humans is encoded by the CD248 gene.

Endosialin is a member of the “Group XIV”, a novel family of C-type lectin transmembrane receptors which play a role not only in cell–cell adhesion processes but also in host defence. This family comprise three other members, CLEC14A, CD93 and Thrombomodulin the latter of which are better characterized.

Excerpted from Wikipedia’s “CD248” article, available under the CC BY-SA 4.0 licence.