CEA cell adhesion molecule 3
Sign in to saveAlso known as carcinoembryonic antigen-related cell adhesion molecule 3, CD66d antigen, carcinoembryonic antigen CGM1, nonspecific cross-reacting antigen, carcinoembryonic antigen gene family member 1, carcinoembryonic antigen related cell adhesion molecule 3, CEACAM3
Carcinoembryonic antigen-related cell adhesion molecule 3 (CEACAM3) also known as CD66d (Cluster of Differentiation 66d), is a member of the carcinoembryonic antigen (CEA) gene family..
In the Vinony graph
Vinony's link graph records 359 inbound references to CEA cell adhesion molecule 3, and connects out to PubMed, Ensembl genome database project and carcinoembryonic antigen.
Vinony files it under Clusters of differentiation and Genes on human chromosome 19.
Vinony links it to 5 Wikipedia language editions.
Protein · UniProt
Cell adhesion molecule CEACAM3
- Gene
- CEACAM3
- Organism
- Homo sapiens (Human)
- Length
- 252 aa
- Molecular mass
- 27,091 Da
- Evidence
- 1: Evidence at protein level
Major granulocyte receptor mediating recognition and efficient opsonin-independent phagocytosis of CEACAM-binding microorganisms, including Neissiria, Moxarella and Haemophilus species, thus playing an important role in the clearance of pathogens by the innate immune system. Responsible for RAC1 stimulation in the course of pathogen phagocytosis
Swiss-Prot (reviewed) · via UniProt
Clinical Trials
1 registeredWikidata facts
- Instance of
- protein
Show 1 more fact
- found in taxon
- Homo sapiens
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
5 sectionsContents
- Use
- See also
- References
- Further reading
- External links
Carcinoembryonic antigen-related cell adhesion molecule 3 (CEACAM3) also known as CD66d (Cluster of Differentiation 66d), is a member of the carcinoembryonic antigen (CEA) gene family..
This gene encodes a member of the family of carcinoembryonic antigen-related cell adhesion molecules (CEACAMs), which are used by several bacterial pathogens to bind and invade host cells. The encoded transmembrane protein directs phagocytosis of several bacterial species that is dependent on the small GTPase Rac. It is thought to serve an important role in controlling human-specific pathogens by the innate immune system. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Excerpted from Wikipedia’s “CEA cell adhesion molecule 3” article, available under the CC BY-SA 4.0 licence.