CD93 molecule
Sign in to saveAlso known as C1qR, C1q receptor 1, C1qRp, C1q/MBL/SPA receptor, complement component C1q receptor, complement component 1 q subcomponent receptor 1, matrix-remodelling associated 4, matrix-remodeling-associated protein 4
CD93 (Cluster of Differentiation 93) is a protein that in humans is encoded by the CD93 gene. CD93 is a C-type lectin transmembrane receptor which plays a role not only in cell–cell adhesion processes but also in host defense.
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Article
7 sectionsContents
- Family
- Expression
- Function
- See also
- References
- Further reading
- External links
CD93 (Cluster of Differentiation 93) is a protein that in humans is encoded by the CD93 gene. CD93 is a C-type lectin transmembrane receptor which plays a role not only in cell–cell adhesion processes but also in host defense.
== Family == CD93 belongs to the Group XIV C-Type lectin family, a group containing three other members, endosialin (CD248), CLEC14A and thrombomodulin, a well characterized anticoagulant. All of them contain a C-type lectin domain, a series of epidermal growth factor like domains, a highly glycosylated mucin-like domain, a unique transmembrane domain and a short cytoplasmic tail. Due to their strong homology and their close proximity on chromosome 20, CD93 has been suggested to have arisen from the thrombomodulin gene through a duplication event.