chymopapain
Sign in to saveChymopapain (, chymopapain A, chymopapain B, chymopapain S, brand name Chymodiactin) is a proteolytic enzyme isolated from the latex of papaya (Carica papaya). It is a cysteine protease which belongs to the papain-like protease (PLCP) group. Because of its proteolytic activity, it is the main molecule in the process of chemonucleolysis, used in some procedures like the treatment of herniated lower lumbar discs in the spine by a nonsurgical method.
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Within Vinony's link graph, chymopapain is referenced by 35 other articles, and connects out to electric charge, PubMed and CAS Registry Number.
It sits within the topics Chemical pages without DrugBank identifier, Chemicals that do not have a ChemSpider ID assigned and Drugboxes which contain changes to verified fields.
Its subject is documented across 5 Wikipedia language editions.
Chemical data
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Unknown
- First approval
- 1982
- Admin. routes
- parenteral
via ChEMBL · EBI
Protein · UniProt
Chymopapain
- Organism
- Carica papaya (Papaya)
- Length
- 352 aa
- Molecular mass
- 39,415 Da
- Evidence
- 1: Evidence at protein level
Cysteine proteinase with a high level of diversity in substrate specificity
Swiss-Prot (reviewed) · via UniProt
Wikidata facts
- Instance of
- protein
- Subclass of
- cysteine protease
Show 3 more facts
- Commons category
- Chymopapain
- EC enzyme number
- 3.4.22.6
- found in taxon
- Carica papaya
Sources (2)
via Wikidata · CC0
~10 min read
Encyclopedic overview
10 sectionsContents
- Structure
- Primary structure
- Secondary and tertiary structures
- Quaternary structure
- Function
- Synthesis
- Medical applications
- See also
- References
- Further reading
Chymopapain (, chymopapain A, chymopapain B, chymopapain S, brand name Chymodiactin) is a proteolytic enzyme isolated from the latex of papaya (Carica papaya). It is a cysteine protease which belongs to the papain-like protease (PLCP) group. Because of its proteolytic activity, it is the main molecule in the process of chemonucleolysis, used in some procedures like the treatment of herniated lower lumbar discs in the spine by a nonsurgical method.
== Structure ==
Excerpted from Wikipedia’s “chymopapain” article, available under the CC BY-SA 4.0 licence.