کلونیدین

Key facts

Drug.image

Clonidine2DACS3.svg

Drug.image_class

skin-invert-image

Drug.width

120

Drug.image2

File:Clonidine ball-and-stick model.png

Drug.image_class2

bg-transparent

Drug.width2

120

Drug.tradename

Catapres, Javadin, Kapvay, others

Drug.MedlinePlus

a682243

Drug.DailyMedID

Clonidine

Drug.pregnancy_AU

B3

Drug.routes_of_administration

By mouth, epidural, intravenous, transdermal, topical

Drug.class

α2-Adrenergic receptor agonist, Imidazoline I1 receptor agonist, Anxiolytic

Drug.ATC_prefix

C02

Drug.ATC_suffix

AC01

Drug.ATC_supplemental

, , ,

Drug.legal_AU

S4

Drug.legal_AU_comment

/Appendix K, clause 1

Drug.legal_CA

Rx-only

via Wikipedia infobox

Chemical data

Formula

C9H9Cl2N3

Molecular weight

230.09 g/mol

IUPAC name

N-(2,6-dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine

SMILES

C1CN=C(N1)NC2=C(C=CC=C2Cl)Cl

InChIKey

GJSURZIOUXUGAL-UHFFFAOYSA-N

XLogP

1.6

Polar surface area

36.4 Ų

H-bond donors

2

H-bond acceptors

1

Formal charge

0

via PubChem

Drug data · ChEMBL

Max clinical phase

Approved

Molecule type

Small molecule

First approval

1974

Admin. routes

oral, parenteral, topical

Indications

attention deficit hyperactivity disorder, hypertension, pain, cardiovascular disease

via ChEMBL · EBI

• Clonidine toxicity revisited.Journal of toxicology. Clinical toxicology · 2002
• Clonidine and alcohol withdrawal.Advances in alcohol & substance abuse · 1987
• Clonidine for smoking cessation.The Cochrane database of systematic reviews · 2004
• Clonidine for smoking cessation.The Cochrane database of systematic reviews · 2000
• Clonidine as a strategy for discontinuing dexmedetomidine sedation in critically ill patients: A narrative review.American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists · 2020

via PubMed

Wikidata facts

Subclass of

chemical compound

Mass

229.017

Has use

medication

via Wikidata · CC0