CLSPN
Sign in to saveAlso known as claspin
Claspin is a protein that in humans is encoded by the CLSPN gene.
Gene data
CLSPN- Name
- claspin
- Type
- protein-coding
- Position
- 35,720,218–35,770,002 (−)
- Ensembl
- ENSG00000092853
- RefSeq RNA
- NM_001190481.2, NM_001330490.2, NM_022111.4
- RefSeq protein
- NP_001177410.1, NP_001317419.1, NP_071394.2
The product of this gene is an essential upstream regulator of checkpoint kinase 1 and triggers a checkpoint arrest of the cell cycle in response to replicative stress or DNA damage. The protein is also required for efficient DNA replication during a normal S phase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 11138
- exact match
- identifiers.org/ncbigene/63967
- genomic end
- 35769978
- genomic start
- 36185819
- cytogenetic location
- 1p34.3
Sources (4)
via Wikidata · CC0
~1 min read
Article
5 sectionsContents
- Function
- Interactions
- References
- External links
- Further reading
Claspin is a protein that in humans is encoded by the CLSPN gene.
== Function ==
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via Wikidata sitelinks · CC0
Connections
Q180686
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human chromosome 1
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Ensembl genome database project
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protein
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Wikidata
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gene
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chromosome
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digital object identifier
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bibcode
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cell cycle
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human genome
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Q229883
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base pair
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locus
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gene expression
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Online Mendelian Inheritance in Man
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Q22908627
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Xenopus
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Entrez
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Q905695
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