Structure via PubChem · Public domain (PubChem)
daledalin
Sign in to saveAlso known as UK-3557-15
Daledalin (UK-3557-15) is an antidepressant which was synthesized and trialed for depression in the early 1970s, but was never marketed. It is a selective norepinephrine reuptake inhibitor, with no significant effects on the reuptake of serotonin and dopamine, and no antihistamine or anticholinergic properties.
Chemical data
- Formula
- C19H24N2
- Molecular weight
- 280.4 g/mol
- IUPAC name
- N-methyl-3-(3-methyl-1-phenyl-2H-indol-3-yl)propan-1-amine
- SMILES
- CC1(CN(C2=CC=CC=C21)C3=CC=CC=C3)CCCNC
- InChIKey
- YFAIJBZEDDOCAN-UHFFFAOYSA-N
- XLogP
- 4.3
- Polar surface area
- 15.3 Ų
- H-bond donors
- 1
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 280.193949
Show 3 more facts
- chemical formula
- C₁₉H₂₄N₂
- canonical SMILES
- CC1(CN(C2=CC=CC=C21)C3=CC=CC=C3)CCCNC
- Commons category
- Daledalin
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- Synthesis
- References
Daledalin (UK-3557-15) is an antidepressant which was synthesized and trialed for depression in the early 1970s, but was never marketed. It is a selective norepinephrine reuptake inhibitor, with no significant effects on the reuptake of serotonin and dopamine, and no antihistamine or anticholinergic properties.
==Synthesis== Daledalin can be prepared by the reduction of amedalin with diborane. thumb|left|500px|class=skin-invert-image|Daledalin synthesis
Excerpted from Wikipedia’s “daledalin” article, available under the CC BY-SA 4.0 licence.