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دی هیدروکدئین

Structure via PubChem · Public domain (PubChem)

EntityQ377270· pop 26· linked from 962 articles

دی هیدروکدئین

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Also known as DF-118, Dicogesic®, dihydrocodeine bitartrate, Drocode, Paracodeine®, Dihydrocodeine, DHC, Remedacen

Dihydrocodeine is a semi-synthetic opioid analgesic prescribed for pain or severe dyspnea, or as an antitussive, either alone or compounded with paracetamol (acetaminophen) (as in co-dydramol) or aspirin. It was developed in Germany in 1908 and first marketed in 1911.

Chemical data

Formula
C18H23NO3
Molecular weight
301.4 g/mol
IUPAC name
(4R,4aR,7S,7aR,12bS)-9-methoxy-3-methyl-2,4,4a,5,6,7,7a,13-octahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-ol
SMILES
CN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)OC)O[C@H]3[C@H](CC4)O
InChIKey
RBOXVHNMENFORY-DNJOTXNNSA-N
XLogP
2.2
Polar surface area
41.9 Ų
H-bond donors
1
H-bond acceptors
4
Formal charge
0

via PubChem

Research

544 papers

via PubMed

Gallery (5)