ไดไฮโดรโคดีอีน
Also known as DF-118, Dicogesic®, dihydrocodeine bitartrate, Drocode, Paracodeine®, Dihydrocodeine, DHC, Remedacen
Dihydrocodeine is a semi-synthetic opioid analgesic prescribed for pain or severe dyspnea, or as an antitussive, either alone or compounded with paracetamol (acetaminophen) (as in co-dydramol) or aspirin. It was developed in Germany in 1908 and first marketed in 1911.
Chemical data
- Formula
- C18H23NO3
- Molecular weight
- 301.4 g/mol
- IUPAC name
- (4R,4aR,7S,7aR,12bS)-9-methoxy-3-methyl-2,4,4a,5,6,7,7a,13-octahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-7-ol
- SMILES
- CN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)OC)O[C@H]3[C@H](CC4)O
- InChIKey
- RBOXVHNMENFORY-DNJOTXNNSA-N
- XLogP
- 2.2
- Polar surface area
- 41.9 Ų
- H-bond donors
- 1
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Research
544 papersvia
Gallery (5)
Connections
Categories
4,5-EpoxymorphinansCatechol ethersCleanup tagged articles with a reason field from August 2014CyclohexanolsDrugboxes which contain changes to verified fieldsDrugboxes which contain changes to watched fieldsECHA InfoCard ID from WikidataGerman inventionsMu-opioid receptor agonistsSemisynthetic opioids