Structure via PubChem · Public domain (PubChem)
(E)-olopatadine
Sign in to saveOlopatadine, sold under the brand name Patanol among others, is an antihistamine medication used to decrease the symptoms of allergic conjunctivitis and allergic rhinitis (hay fever). It is used as eye drops or as a nasal spray. The eye drops generally result in an improvement within half an hour.
Chemical data
- Formula
- C21H23NO3
- Molecular weight
- 337.4 g/mol
- IUPAC name
- 2-[(11E)-11-[3-(dimethylamino)propylidene]-6H-benzo[c][1]benzoxepin-2-yl]acetic acid
- SMILES
- CN(C)CC/C=C/1\C2=CC=CC=C2COC3=C1C=C(C=C3)CC(=O)O
- InChIKey
- JBIMVDZLSHOPLA-QGMBQPNBSA-N
- XLogP
- 1.5
- Polar surface area
- 49.8 Ų
- H-bond donors
- 1
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Mass
- 337.16779359599997
- Has use
- medication
Show 3 more facts
- canonical SMILES
- CN(C)CCC=C1C2=CC=CC=C2COC3=C1C=C(C=C3)CC(=O)O
- chemical formula
- C₂₁H₂₃NO₃
- isomeric SMILES
- CN(C)CC/C=C/1\C2=CC=CC=C2COC3=C1C=C(C=C3)CC(=O)O
Sources (2)
via Wikidata · CC0
~6 min read
Encyclopedic overview
11 sectionsContents
- Medical uses
- Side effects
- Chemistry
- Synthesis
- Pharmacology
- Pharmacodynamics
- History
- Society and culture
- Brand names
- References
- External links
{{Drugbox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 462265189 | image = Olopatadine.svg | image_class = skin-invert-image | width = | alt = | caption =
| pronounce = | tradename = Patanol, Pataday, Opatanol | Drugs.com = | MedlinePlus = a602025 | DailyMedID = Olopatadine | pregnancy_AU = B1 | pregnancy_AU_comment = | pregnancy_category= | routes_of_administration = Eye drops, nasal spray | ATC_prefix = S01 | ATC_suffix = GX09 | ATC_supplemental =
Excerpted from Wikipedia’s “(E)-olopatadine” article, available under the CC BY-SA 4.0 licence.