EIF2B3
Sign in to saveAlso known as EIF-2B, EIF2Bgamma, eukaryotic translation initiation factor 2B subunit gamma
Translation initiation factor eIF-2B subunit gamma is a protein that in humans is encoded by the EIF2B3 gene.
In the Vinony graph
Vinony's link graph records 209 inbound references to EIF2B3, and connects out to PubMed, translation and human chromosome 1.
It is catalogued under the topic Genes on human chromosome 1.
Vinony links it to 6 Wikipedia language editions.
Gene data
EIF2B3- Name
- eukaryotic translation initiation factor 2B subunit gamma
- Type
- protein-coding
- Position
- 44,850,464–44,986,722 (−)
- Aliases
- EIF-2B, EIF2Bgamma, VWM3
- Ensembl
- ENSG00000070785
- RefSeq RNA
- NM_001166588.3, NM_001261418.2, NM_020365.5, XM_047433499.1, XM_047433500.1
- RefSeq protein
- NP_001160060.1, NP_001248347.1, NP_065098.1, XP_047289455.1, XP_047289456.1
The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
eukaryotic translation initiation factor 2B subunit gamma
- Symbol
- EIF2B3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:44,850,464-44,986,722
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 7005
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/8891
- genomic end
- 45452282
- genomic start
- 45316450
- chromosome
- human chromosome 1
- cytogenetic location
- 1p34.1
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Translation initiation factor eIF-2B subunit gamma is a protein that in humans is encoded by the EIF2B3 gene.
==References==
Excerpted from Wikipedia’s “EIF2B3” article, available under the CC BY-SA 4.0 licence.