Skip to content
GeneQ18033508· pop 6· linked from 209 articles

Also known as EIF-2B, EIF2Bgamma, eukaryotic translation initiation factor 2B subunit gamma

Translation initiation factor eIF-2B subunit gamma is a protein that in humans is encoded by the EIF2B3 gene.

Gene data

EIF2B3
Name
eukaryotic translation initiation factor 2B subunit gamma
Type
protein-coding
Aliases
EIF-2B, EIF2Bgamma, VWM3

The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009].

via MyGene.info

Wikidata facts

Show 5 more facts
HomoloGene ID
7005
genomic end
45452282
genomic start
45316450
cytogenetic location
1p34.1
Sources (4)

via Wikidata · CC0

~1 min read

Article

2 sections
Contents
  • References
  • Further reading

Translation initiation factor eIF-2B subunit gamma is a protein that in humans is encoded by the EIF2B3 gene.

==References==

Available in 6 languages

via Wikidata sitelinks · CC0

Connections

Categories