EIF2S2
Sign in to saveAlso known as EIF2, EIF2B, EIF2beta, PPP1R67, eIF-2-beta, eukaryotic translation initiation factor 2 subunit beta
Eukaryotic translation initiation factor 2 subunit 2 (eIF2β) is a protein that in humans is encoded by the EIF2S2 gene.
Gene data
EIF2S2- Name
- eukaryotic translation initiation factor 2 subunit beta
- Type
- protein-coding
- Aliases
- EIF2, EIF2B, EIF2beta, PPP1R67, eIF-2-beta
Eukaryotic translation initiation factor 2 (EIF-2) functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA and binding to a 40S ribosomal subunit. EIF-2 is composed of three subunits, alpha, beta, and gamma, with the protein encoded by this gene representing the beta subunit. The beta subunit catalyzes the exchange of GDP for GTP, which recycles the EIF-2 complex for another round of initiation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015].
via MyGene.info
Gene · Ensembl
eukaryotic translation initiation factor 2 subunit beta
- Symbol
- EIF2S2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 20:34,088,309-34,112,284
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 2904
- exact match
- identifiers.org/ncbigene/8894
- genomic end
- 34112243
- genomic start
- 34088309
- cytogenetic location
- 20q11.22
Sources (4)
via Wikidata · CC0
~1 min read
Article
5 sectionsContents
- Function
- Regulation
- See also
- References
- Further reading
Eukaryotic translation initiation factor 2 subunit 2 (eIF2β) is a protein that in humans is encoded by the EIF2S2 gene.
==Function==