EIF2B4
Sign in to saveAlso known as EIF-2B, EIF2B, EIF2Bdelta, eukaryotic translation initiation factor 2B subunit delta
Translation initiation factor eIF-2B subunit delta is a protein that in humans is encoded by the EIF2B4 gene.
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Vinony's link graph records 210 inbound references to EIF2B4, and connects out to PubMed, translation and human chromosome 2.
It is catalogued under the topic Genes on human chromosome 2.
Vinony links it to 5 Wikipedia language editions.
Gene data
EIF2B4- Name
- eukaryotic translation initiation factor 2B subunit delta
- Type
- protein-coding
- Position
- 27,363,420–27,370,466 (−)
- Aliases
- EIF-2B, EIF2B, EIF2Bdelta, VWM4
- Ensembl
- ENSG00000115211
- RefSeq RNA
- NM_001034116.2, NM_001318965.2, NM_001318966.2, NM_001318967.2, NM_001318968.2
- RefSeq protein
- NP_001029288.1, NP_001305894.1, NP_001305895.1, NP_001305896.1, NP_001305897.1
Eukaryotic initiation factor 2B (EIF2B), which is necessary for protein synthesis, is a GTP exchange factor composed of five different subunits. The protein encoded by this gene is the fourth, or delta, subunit. Defects in this gene are a cause of leukoencephalopathy with vanishing white matter (VWM) and ovarioleukodystrophy. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
eukaryotic translation initiation factor 2B subunit delta
- Symbol
- EIF2B4
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 2:27,363,420-27,370,466
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 5976
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/8890
- genomic end
- 27370338
- genomic start
- 27587219
- chromosome
- human chromosome 2
- cytogenetic location
- 2p23.3
- genetic association
- leukoencephalopathy with vanishing white matter
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Translation initiation factor eIF-2B subunit delta is a protein that in humans is encoded by the EIF2B4 gene.
==References==
Excerpted from Wikipedia’s “EIF2B4” article, available under the CC BY-SA 4.0 licence.