EPGN
Sign in to saveAlso known as ALGV3072, EPG, PRO9904, epithelial mitogen
Epigen also known as epithelial mitogen is a protein that in humans is encoded by the EPGN gene.
In the Vinony graph
Within Vinony's link graph, EPGN is referenced by 354 other articles, and connects out to PubMed, Ensembl genome database project and protein.
It is catalogued under the topic Genes on human chromosome 4.
Its subject is documented across 5 Wikipedia language editions.
Gene data
EPGN- Name
- epithelial mitogen
- Type
- protein-coding
- Position
- 74,308,464–74,317,297 (+)
- Aliases
- ALGV3072, EPG, PRO9904
- Ensembl
- ENSG00000182585
- RefSeq RNA
- NM_001013442.2, NM_001270989.2, NM_001270990.2, NM_001270991.2, NM_001270992.2
- RefSeq protein
- NP_001013460.1, NP_001257918.1, NP_001257919.1, NP_001257920.1, NP_001257921.1
The protein encoded by this gene is a member of the epidermal growth factor family. Members of this family are ligands for the epidermal growth factor receptor and play a role in cell survival, proliferation and migration. This protein has been reported to have high mitogenic activity but low affinity for its receptor. Expression of this transcript and protein have been reported in cancer specimens of the breast, bladder, and prostate. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
epithelial mitogen
- Symbol
- EPGN
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 4:74,308,464-74,317,297
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 19527
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/255324
- genomic end
- 74316789
- genomic start
- 74308470
- chromosome
- human chromosome 4
- cytogenetic location
- 4q13.3
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Function
- References
- External links
Epigen also known as epithelial mitogen is a protein that in humans is encoded by the EPGN gene.
== Function == The protein encoded by this gene is a member of the epidermal growth factor family. Members of this family are ligands for the epidermal growth factor receptor and play a role in cell survival, proliferation and migration. This protein has been reported to have high mitogenic activity but low affinity for its receptor. Expression of this transcript and protein have been reported in cancer specimens of the breast, bladder, and prostate.
Excerpted from Wikipedia’s “EPGN” article, available under the CC BY-SA 4.0 licence.