GABRG2

Also known as CAE2, ECA2, GEFSP3, gamma-aminobutyric acid type A receptor gamma2 subunit, EIEE74, FEB8

protein-coding gene in the species Homo sapiens

In the Vinony graph

Within Vinony's link graph, GABRG2 is referenced by 109 other articles, and connects out to PubMed, Ensembl genome database project and protein.

It sits within the topics Genes on human chromosome 5 and Ion channels.

Its subject is documented across 5 Wikipedia language editions.

Gene data

GABRG2

Name: gamma-aminobutyric acid type A receptor subunit gamma2
Type: protein-coding
Position: 162,000,057–162,162,977 (+)
Aliases: CAE2, DEE74, ECA2, EIEE74, FEB8, GEFSP3
Ensembl: ENSG00000113327
RefSeq RNA: NM_000816.3, NM_001375339.1, NM_001375340.1, NM_001375341.1, NM_001375342.1
RefSeq protein: NP_000807.2, NP_001362268.1, NP_001362269.1, NP_001362270.1, NP_001362271.1

This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].