GATA3 is a transcription factor that in humans is encoded by the GATA3 gene. Studies in animal models and humans indicate that it controls the expression of a wide range of biologically and clinically important genes.
GATA3 is a transcription factor that in humans is encoded by the GATA3 gene. Studies in animal models and humans indicate that it controls the expression of a wide range of biologically and clinically important genes.
The GATA3 transcription factor is critical for the embryonic development of various tissues as well as for inflammatory and humoral immune responses and the proper functioning of the endothelium of blood vessels. The GATA factors, GATA1 to GATA6 are a family of zinc finger transcription factors that bind to a consensus DNA sequence (A/T)-G-A-T-A-(A/G) in gene promoters and enhancers. GATA3 plays central role in allergy and immunity against worm infections. GATA3 haploinsufficiency (i.e. loss of one or the two inherited GATA3 genes) results in a congenital disorder termed the Barakat syndrome.
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).