ADGRA1
Sign in to saveAlso known as GPR123, adhesion G protein-coupled receptor A1
Probable G-protein coupled receptor 123 is a protein that in humans is encoded by the GPR123 gene. It is a member of the adhesion-GPCR family of receptors. Family members are normally characterized by an extended extracellular region with a variable number of protein domains coupled to a TM7 domain via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.
In the Vinony graph
Vinony's link graph records 484 inbound references to ADGRA1, and connects out to PubMed, Ensembl genome database project and cell surface receptor.
Vinony files it under Genes on human chromosome 10 and G protein-coupled receptors.
Vinony links it to 6 Wikipedia language editions.
Gene data
ADGRA1- Name
- adhesion G protein-coupled receptor A1
- Type
- protein-coding
- Position
- 133,087,814–133,131,675 (+)
- Aliases
- GPR123
- Ensembl
- ENSG00000197177
- RefSeq RNA
- NM_001083909.3, NM_001291085.2, NM_032422.2, XM_011540273.1, XM_017016779.2
- RefSeq protein
- NP_001077378.1, NP_001278014.1, XP_011538575.1, XP_016872268.1, XP_054222921.1
This gene encodes a protein that belongs to the adhesion family of G-protein-coupled receptors. Members of this family function in several sensory systems and regulate blood pressure, immune responses, food intake and development. A similar protein in rodents is thought to play a role in in the regulation of neuronal signaling pathways. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Mar 2014].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
adhesion G protein-coupled receptor A1
- Symbol
- ADGRA1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 10:133,087,814-133,131,675
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 18582
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/84435
- genomic end
- 134945179
- genomic start
- 133087924
- chromosome
- human chromosome 10
- cytogenetic location
- 10q26.3
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Probable G-protein coupled receptor 123 is a protein that in humans is encoded by the GPR123 gene. It is a member of the adhesion-GPCR family of receptors. Family members are normally characterized by an extended extracellular region with a variable number of protein domains coupled to a TM7 domain via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.
==References==
Excerpted from Wikipedia’s “ADGRA1” article, available under the CC BY-SA 4.0 licence.
Available in 6 languages
via Wikidata sitelinks · CC0