haloprogin

Also known as Halotex, M-1028, Haloprogina, Haloprogine, Haloproginum

Haloprogin is an antifungal drug used to treat athlete's foot and other fungal infections. It is marketed in creams under the trade names Halotex, Mycanden, Mycilan, and Polik.

Chemical data

Formula: C9H4Cl3IO
Molecular weight: 361.4 g/mol
IUPAC name: 1,2,4-trichloro-5-(3-iodoprop-2-ynoxy)benzene
SMILES: C1=C(C(=CC(=C1Cl)Cl)Cl)OCC#CI
InChIKey: CTETYYAZBPJBHE-UHFFFAOYSA-N
XLogP: 4.6
Polar surface area: 9.2 Å²
H-bond donors: 0
H-bond acceptors: 1
Formal charge: 0

via PubChem

Drug data · ChEMBL

Max clinical phase: Approved
Molecule type: Small molecule
First approval: 1982
Admin. routes: topical

via ChEMBL · EBI

Research

45 papers

Superficial mycoses.The Journal of investigative dermatology · 1976
Haloprogin: a topical antifungal agent.Applied microbiology · 1970
Haloprogin therapy for dermatophyte infections.Archives of dermatology · 1972
Clinical evaluation of haloprogin.Toxicology and applied pharmacology · 1972
Haloprogin as treatment for fungal infections.Clinical and experimental dermatology · 1979

via PubMed

Wikidata facts

Subclass of: chemical compound
Mass: 359.837246
Has use: medication

Show 5 more facts

chemical formula: C₉H₄Cl₃IO
medical condition treated: tinea
canonical SMILES: C1=C(C(=CC(=C1Cl)Cl)Cl)OCC#CI
subject has role: antifungal
Commons category: Haloprogin

Sources (2)

via Wikidata · CC0

~1 min read

Encyclopedic overview

2 sections

Contents

Action
References

Haloprogin is an antifungal drug used to treat athlete's foot and other fungal infections. It is marketed in creams under the trade names Halotex, Mycanden, Mycilan, and Polik.

==Action== Haloprogin was previously used in 1% topical creams as an antifungal agent. It was marketed over-the-counter primarily to treat tinea infections of the skin. The mechanism of action is unknown.

Excerpted from Wikipedia’s “haloprogin” article, available under the CC BY-SA 4.0 licence.

Available in 9 languages

via Wikidata sitelinks · CC0