HM13
Sign in to saveAlso known as H13, IMP1, IMPAS, IMPAS-1, MSTP086, PSENL3, PSL3, SPP
Minor histocompatibility antigen H13 is a protein that in humans is encoded by the HM13 gene.
In the Vinony graph
Vinony's link graph records 2 inbound references to HM13, and connects out to PubMed, human chromosome 20 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 20.
Vinony links it to 5 Wikipedia language editions.
Gene data
HM13- Name
- histocompatibility minor 13
- Type
- protein-coding
- Position
- 31,514,370–31,577,923 (+)
- Aliases
- H13, HM13-IT1, IMP1, IMPAS, IMPAS-1, MSTP086, PSENL3, PSL3, SPP, SPPL1
- Ensembl
- ENSG00000101294
- RefSeq RNA
- NM_030789.4, NM_178580.3, NM_178581.3, NM_178582.3
- RefSeq protein
- NP_110416.1, NP_848695.1, NP_848696.1, NP_848697.1
The protein encoded by this gene, which localizes to the endoplasmic reticulum, catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein. This activity is required to generate signal sequence-derived human lymphocyte antigen-E epitopes that are recognized by the immune system, and to process hepatitis C virus core protein. The encoded protein is an integral membrane protein with sequence motifs characteristic of the presenilin-type aspartic proteases. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
histocompatibility minor 13
- Symbol
- HM13
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 20:31,514,370-31,577,923
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 7749
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/81502
- genomic end
- 30157370
- genomic start
- 31514410
- chromosome
- human chromosome 20
- cytogenetic location
- 20q11.21
Sources (4)
via Wikidata · CC0
~2 min read
Encyclopedic overview
3 sectionsContents
- Function
- References
- Further reading
Minor histocompatibility antigen H13 is a protein that in humans is encoded by the HM13 gene.
== Function ==
Excerpted from Wikipedia’s “HM13” article, available under the CC BY-SA 4.0 licence.