胰岛素抵抗

Key facts

Specialty

Endocrinology

Complications

Nonalcoholic fatty liver disease , vascular disease .

Duration

10 to 15 years before developing type 2 diabetes.

Causes

Lipotoxicity , use of glucocorticoids , anti-adrenergic , protease inhibitors , selective serotonin reuptake inhibitors , atypical antipsychotics .

Risk factors

Hyperinsulinemia

Diagnostic method

Glucose challenge test , Glucose clamp technique .

Prognosis

Hyperglycemia , hypertension , dyslipidemia , hyperuricemia , elevated inflammatory markers , endothelial dysfunction , a prothrombotic state, and polycystic ovary syndrome (PCOS).

via Wikipedia infobox

• Insulin Resistance: From Mechanisms to Therapeutic Strategies.Diabetes & metabolism journal · 2022
• Insulin resistance in type 2 diabetes mellitus.