KCNA5

Name

potassium voltage-gated channel subfamily A member 5

Type

protein-coding

Position

5,043,879–5,052,613 (+)

Aliases

ATFB7, HCK1, HK2, HPCN1, KV1.5, PCN1

Ensembl

ENSG00000130037

RefSeq RNA

NM_002234.4

RefSeq protein

NP_002225.2

Potassium channels represent the most complex class of voltage-gated ino channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, the function of which could restore the resting membrane potential of beta cells after depolarization and thereby contribute to the regulation of insulin secretion. This gene is intronless, and the gene is clustered with genes KCNA1 and KCNA6 on chromosome 12. Defects in this gene are a cause of familial atrial fibrillation type 7 (ATFB7). [provided by RefSeq, May 2012].

via MyGene.info

Gene · Ensembl

potassium voltage-gated channel subfamily A member 5

Symbol

KCNA5

Biotype

Protein coding

Organism

Homo sapiens

Location

12:5,043,879-5,052,613

Strand

Forward (+)

Assembly

GRCh38