KLK10
Sign in to saveAlso known as NES1, PRSSL1, kallikrein related peptidase 10
Kallikrein-10 is a protein that in humans is encoded by the KLK10 gene.
Gene data
KLK10- Name
- kallikrein related peptidase 10
- Type
- protein-coding
- Position
- 51,012,739–51,021,048 (−)
- Aliases
- NES1, PRSSL1
- Ensembl
- ENSG00000129451
- RefSeq RNA
- NM_001077500.2, NM_002776.5, NM_145888.3, XM_005259061.4, XM_005259062.4
- RefSeq protein
- NP_001070968.1, NP_002767.2, NP_665895.1, XP_005259118.1, XP_005259119.1
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 26428
- exact match
- identifiers.org/ncbigene/5655
- genomic start
- 51515995
- genomic end
- 51523431
- cytogenetic location
- 19q13.41
Sources (4)
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- References
- Further reading
- External links
Kallikrein-10 is a protein that in humans is encoded by the KLK10 gene.
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.