KLK15
Sign in to saveAlso known as ACO, HSRNASPH, kallikrein related peptidase 15
Kallikrein-15 is a protein that in humans is encoded by the KLK15 gene.
In the Vinony graph
Within Vinony's link graph, KLK15 is referenced by 138 other articles, and connects out to PubMed, human chromosome 19 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 19.
Its subject is documented across 5 Wikipedia language editions.
Gene data
KLK15- Name
- kallikrein related peptidase 15
- Type
- protein-coding
- Position
- 50,825,289–50,837,213 (−)
- Aliases
- ACO, HSRNASPH
- Ensembl
- ENSG00000174562
- RefSeq RNA
- NM_001277081.2, NM_001277082.2, NM_017509.4, NM_023006.1, NM_138563.1
- RefSeq protein
- NP_001264010.1, NP_001264011.1, NP_059979.2, XP_011525389.1, XP_011525390.1
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. In prostate cancer, this gene has increased expression, which indicates its possible use as a diagnostic or prognostic marker for prostate cancer. The gene contains multiple polyadenylation sites and alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
via MyGene.info
Gene · Ensembl
kallikrein related peptidase 15
- Symbol
- KLK15
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:50,825,289-50,837,213
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 77571
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/55554
- genomic end
- 51340469
- genomic start
- 51328545
- chromosome
- human chromosome 19
- cytogenetic location
- 19q13.33
- expressed in
- pericardium
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- Further reading
- External links
Kallikrein-15 is a protein that in humans is encoded by the KLK15 gene.
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. In prostate cancer, this gene has increased expression, which indicates its possible use as a diagnostic or prognostic marker for prostate cancer. The gene contains multiple polyadenylation sites and alternative splicing results in multiple transcript variants encoding distinct isoforms.
Excerpted from Wikipedia’s “KLK15” article, available under the CC BY-SA 4.0 licence.