ليسوريد

Chemical data

Formula

C20H26N4O

Molecular weight

338.4 g/mol

IUPAC name

3-[(6aR,9S)-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinolin-9-yl]-1,1-diethylurea

SMILES

CCN(CC)C(=O)N[C@@H]1CN([C@@H]2CC3=CNC4=CC=CC(=C34)C2=C1)C

InChIKey

BKRGVLQUQGGVSM-KBXCAEBGSA-N

XLogP

2.7

Polar surface area

51.4 Ų

H-bond donors

2

H-bond acceptors

2

Formal charge

0

via PubChem

Drug data · ChEMBL

Max clinical phase

Phase 3

Molecule type

Small molecule

Indications

cocaine dependence, restless legs syndrome, Parkinson disease, migraine disorder

via ChEMBL · EBI

• Are the LSD-analogs lisuride and ergotamine examples of non-hallucinogenic serotonin 5-HT2A receptor agonists?Journal of psychopharmacology (Oxford, England) · 2025
• Lisuride for levodopa-induced complications in Parkinson's disease.The Cochrane database of systematic reviews · 2000
• Lisuride in parkinsonism.Annals of neurology · 1981
• Lisuride, a dopamine receptor agonist with 5-HT2B receptor antagonist properties: absence of cardiac valvulopathy adverse drug reaction reports supports the concept of a crucial role for 5-HT2B receptor agonism in cardiac valvular fibrosis.Clinical neuropharmacology · 2006
• Lisuride versus bromocriptine for levodopa-induced complications in Parkinson's disease.The Cochrane database of systematic reviews · 2000

via PubMed

Wikidata facts

Subclass of

chemical compound

Mass

338.210661

Has use

medication

via Wikidata · CC0