Structure via PubChem · Public domain (PubChem)
Lisurid
Sign in to saveAlso known as (+)-lisuride, Dopergin®, lysuride, N'-((8alpha)-9,10-Didehydro-6-methylergolin-8-yl)-N,N-diethylurea, Lisuride, Lisuridum, Lisurida
Arzneistoff
Chemical data
- Formula
- C20H26N4O
- Molecular weight
- 338.4 g/mol
- IUPAC name
- 3-[(6aR,9S)-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinolin-9-yl]-1,1-diethylurea
- SMILES
- CCN(CC)C(=O)N[C@@H]1CN([C@@H]2CC3=CNC4=CC=CC(=C34)C2=C1)C
- InChIKey
- BKRGVLQUQGGVSM-KBXCAEBGSA-N
- XLogP
- 2.7
- Polar surface area
- 51.4 Ų
- H-bond donors
- 2
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 3
- Molecule type
- Small molecule
- Indications
- cocaine dependence, restless legs syndrome, Parkinson disease, migraine disorder
via ChEMBL · EBI
Research
1,030 papers- Are the LSD-analogs lisuride and ergotamine examples of non-hallucinogenic serotonin 5-HT2A receptor agonists?Journal of psychopharmacology (Oxford, England) · 2025
- Lisuride for levodopa-induced complications in Parkinson's disease.The Cochrane database of systematic reviews · 2000
- Lisuride in parkinsonism.Annals of neurology · 1981
- Lisuride, a dopamine receptor agonist with 5-HT2B receptor antagonist properties: absence of cardiac valvulopathy adverse drug reaction reports supports the concept of a crucial role for 5-HT2B receptor agonism in cardiac valvular fibrosis.Clinical neuropharmacology · 2006
- Lisuride versus bromocriptine for levodopa-induced complications in Parkinson's disease.The Cochrane database of systematic reviews · 2000
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 338.210661
- Has use
- medication
Show 7 more facts
- subject has role
- serotonin receptor agonists
- isomeric SMILES
- CCN(CC)C(=O)N[C@@H]1CN([C@@H]2CC3=CNC4=CC=CC(=C34)C2=C1)C
- canonical SMILES
- CCN(CC)C(=O)NC1CN(C2CC3=CNC4=CC=CC(=C34)C2=C1)C
- chemical formula
- C₂₀H₂₆N₄O
- defined daily dose
- 0.6
- World Health Organisation international non-proprietary name
- lisuride
- Commons category
- Lisuride
via Wikidata · CC0
Article · Deutsch
Lisurid ist ein Arzneistoff, der in der Therapie des Morbus Parkinson, in der Prophylaxe der Migräne und als Prolaktinhemmer zum Abstillen eingesetzt wurde. Lisurid wurde in Deutschland unter dem Markennamen Dopergin vertrieben und unterlag der ärztlichen Verschreibungspflicht.
Abstract from DBpedia / Wikipedia · CC BY-SA