Structure via PubChem · Public domain (PubChem)
ممانتین
Sign in to saveAlso known as 3,5-dimethyl-1-adamantanamine, 1,3-dimethyl-5-adamantanamine, 3,5-dimethyl-1-aminoadamantane, 3,5-dimethyltricyclo[3.3.1.1(3,7)]decan-1-amine, 1-amino-3,5-dimethyladamantane, 1,3-dimethylaminoadamantane
Memantine, sold under the brand name Namenda among others, is a medication used to slow the progression of moderate-to-severe Alzheimer's disease. It is taken by mouth.
Chemical data
- Formula
- C12H21N
- Molecular weight
- 179.3 g/mol
- IUPAC name
- 3,5-dimethyladamantan-1-amine
- SMILES
- CC12CC3CC(C1)(CC(C3)(C2)N)C
- InChIKey
- BUGYDGFZZOZRHP-UHFFFAOYSA-N
- XLogP
- 3.3
- Polar surface area
- 26 Ų
- H-bond donors
- 1
- H-bond acceptors
- 1
- Formal charge
- 0
via PubChem
Research
5,145 papers- Mechanism of action of memantine.Current opinion in pharmacology · 2006
- Cholinesterase inhibitors and memantine for the treatment of Alzheimer and non-Alzheimer dementias.Ideggyogyaszati szemle · 2021
- Memantine.Drugs & aging · 2003
- Memantine: Updating a rare success story in pro-cognitive therapeutics.Neuropharmacology · 2024
- Memantine Derivatives as Multitarget Agents in Alzheimer's Disease.Molecules (Basel, Switzerland) · 2020
via PubMed
Described at
Memantine: a medicine to treat some types of dementia. - NHS
NHS medicines information on memantine – what it's used for, side effects, dosage and who can take it.
nhs.uk →Link to a page describing this subject · 2,355 chars · not written by Vinony
Wikidata facts
- Has part
- carbon
- Mass
- 179.1674
- Has use
- medication
Show 8 more facts
- Commons category
- Memantine
- medical condition treated
- Alzheimer's disease
- chemical formula
- C₁₂H₂₁N
- canonical SMILES
- CC12CC3CC(C1)(CC(C3)(C2)N)C
- World Health Organisation international non-proprietary name
- memantine
- defined daily dose
- 40
- subject has role
- dopaminergic
- described at URL
- www.healthline.com/health/drugs/memantine-oral-tablet
Sources (7)
via Wikidata · CC0