moexipril

Also known as RS-10085, SPM-925

Moexipril was an angiotensin converting enzyme inhibitor (ACE inhibitor) used for the treatment of hypertension and congestive heart failure. Moexipril can be administered alone or with other antihypertensives or diuretics.

Chemical data

Formula: C27H34N2O7
Molecular weight: 498.6 g/mol
IUPAC name: (3S)-2-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-3-carboxylic acid
SMILES: CCOC(=O)[C@H](CCC1=CC=CC=C1)N[C@@H](C)C(=O)N2CC3=CC(=C(C=C3C[C@H]2C(=O)O)OC)OC
InChIKey: UWWDHYUMIORJTA-HSQYWUDLSA-N
XLogP: 1.2
Polar surface area: 114 Å²
H-bond donors: 2
H-bond acceptors: 8
Formal charge: 0

via PubChem

Research

124 papers

Moexipril.2012
Moexipril.2006
Moexipril and left ventricular hypertrophy.Vascular health and risk management · 2007
Drugs for hypertension.The Medical letter on drugs and therapeutics · 2024
Moexipril. A review of its use in the management of essential hypertension.Drugs · 1998

via PubMed

Wikidata facts

Mass: 498.236601

Show 6 more facts

chemical formula: C₂₇H₃₄N₂O₇
Commons category: Moexipril
World Health Organisation international non-proprietary name: moexipril
defined daily dose: 15
isomeric SMILES: CCOC(=O)[C@H](CCC1=CC=CC=C1)N[C@@H](C)C(=O)N2CC3=CC(=C(C=C3C[C@H]2C(=O)O)OC)OC
canonical SMILES: CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2CC3=CC(=C(C=C3CC2C(=O)O)OC)OC

Sources (5)

via Wikidata · CC0

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