Structure via PubChem · Public domain (PubChem)
moexipril
Sign in to saveAlso known as RS-10085, SPM-925
Moexipril was an angiotensin converting enzyme inhibitor (ACE inhibitor) used for the treatment of hypertension and congestive heart failure. Moexipril can be administered alone or with other antihypertensives or diuretics.
Chemical data
- Formula
- C27H34N2O7
- Molecular weight
- 498.6 g/mol
- IUPAC name
- (3S)-2-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-3-carboxylic acid
- SMILES
- CCOC(=O)[C@H](CCC1=CC=CC=C1)N[C@@H](C)C(=O)N2CC3=CC(=C(C=C3C[C@H]2C(=O)O)OC)OC
- InChIKey
- UWWDHYUMIORJTA-HSQYWUDLSA-N
- XLogP
- 1.2
- Polar surface area
- 114 Ų
- H-bond donors
- 2
- H-bond acceptors
- 8
- Formal charge
- 0
via PubChem
Research
124 papers- Moexipril.2012
- Moexipril.2006
- Moexipril and left ventricular hypertrophy.Vascular health and risk management · 2007
- Drugs for hypertension.The Medical letter on drugs and therapeutics · 2024
- Moexipril. A review of its use in the management of essential hypertension.Drugs · 1998
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 498.236601
- Has use
- medication
Show 9 more facts
- chemical formula
- C₂₇H₃₄N₂O₇
- Commons category
- Moexipril
- World Health Organisation international non-proprietary name
- moexipril
- medical condition treated
- arterial hypertension
- defined daily dose
- 15
- isomeric SMILES
- CCOC(=O)[C@H](CCC1=CC=CC=C1)N[C@@H](C)C(=O)N2CC3=CC(=C(C=C3C[C@H]2C(=O)O)OC)OC
- canonical SMILES
- CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2CC3=CC(=C(C=C3CC2C(=O)O)OC)OC
- subject has role
- antihypertensive drug
- physically interacts with
- angiotensin I converting enzyme
via Wikidata · CC0
~4 min read
Encyclopedic overview
5 sectionsContents
- Side effects
- Mechanism of action
- Pharmacology
- Synthesis
- References
Moexipril was an angiotensin converting enzyme inhibitor (ACE inhibitor) used for the treatment of hypertension and congestive heart failure. Moexipril can be administered alone or with other antihypertensives or diuretics.
It works by inhibiting the conversion of angiotensin I to angiotensin II.
Excerpted from Wikipedia’s “moexipril” article, available under the CC BY-SA 4.0 licence.