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Morphin

File:Morphine.svg · Wikimedia Commons · See Wikimedia Commons

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Morphin

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Also known as (-)-morphine, (5R,6S,9R,13S,14R)-4,5-epoxy-N-methyl-7-morphinen-3,6-diol, Morphia, morphium, (5alpha,6alpha)-17-methyl-7,8-didehydro-4,5-epoxymorphinan-3,6-diol, (5alpha,6alpha)-didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol, (5α,6α)-didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol, (7R,7AS,12bs)-3-methyl-2,3,4,4a,7,7a-hexahydro-1H-4,12-methano[1]benzofuro[3,2-e]isoquinoline-7,9-diol

organische Verbindung, Opioid, Suchtmittel, Arzneimittel

OverviewAI-generated

Morphine is a chemical compound with the formula C₁₇H₁₉NO₃. It was discovered in 1804. The compound has a mass of 285.136 and a melting point of 254. Its defined daily dose is 30.

The IUPAC name for morphine is (4R,4aR,7S,7aR,12bS)-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7,9-diol. It possesses a charge of 0, an xlogp of 0.8, and a tpsa of 52.9. The molecule contains two hydrogen bond donors and four hydrogen bond acceptors.

Synthesized by Vinony from 21 facts across 4 sources: Wikidata, PubChem, PubMed, Vinony graph. Generated from structured data (not the Wikipedia text) and checked against those facts — may still contain errors.

Key facts

Drug.verifiedrevid
477170110
Drug.image
Morphine2DCSDS.svg
Drug.image_class
skin-invert-image
Drug.width
180
Drug.image2
Morphine molecule ball.png
Drug.image_class2
bg-transparent
Drug.tradename
Statex, MS Contin, Kadian, Oramorph, M-ESLON, others
Drug.MedlinePlus
a682133
Drug.DailyMedID
Morphine
Drug.pregnancy_AU
C
Drug.dependency_liability
High
Drug.addiction_liability
High
Drug.routes_of_administration
Inhalation, insufflation, by mouth, rectal, subcutaneous, intramuscular, intravenous, epidural, intrathecal
Drug.class
Opiate
Drug.ATC_prefix
N02
Drug.ATC_suffix
AA01
Drug.legal_AU
S8
Drug.legal_BR
A1

via Wikipedia infobox

Chemical data

Formula
C17H19NO3
Molecular weight
285.34 g/mol
IUPAC name
(4R,4aR,7S,7aR,12bS)-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7,9-diol
SMILES
CN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)O)O[C@H]3[C@H](C=C4)O
InChIKey
BQJCRHHNABKAKU-KBQPJGBKSA-N
XLogP
0.8
Polar surface area
52.9 Ų
H-bond donors
2
H-bond acceptors
4
Formal charge
0

via PubChem

Research

82,258 papers

via PubMed

Article · Deutsch

Morphin oder Morphium ist ein Hauptalkaloid des Opiums und zählt damit zu den Opiaten. Es gehört zu der Gruppe der stark wirkenden Opioide der Stufe III im WHO-Stufenschema (Klassifizierung der Schmerztherapie) und ist als Schmerzmittel bei starken und stärksten Schmerzen zugelassen. Morphin ist das erste in Reinform isolierte Alkaloid. Das Opioid-Analgetikum ist zudem ein Rauschgift und unterliegt betäubungsmittelrechtlichen Vorschriften gemäß dem Einheitsabkommen über die Betäubungsmittel.

Abstract from DBpedia / Wikipedia · CC BY-SA

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