نفازودون

Also known as BMY-13754, MJ-13754-1, 1-{3-[4-(m-chlorophenyl)-1-piperazinyl]propyl}-3-ethyl-4-(2-phenoxyethyl)-delta2-1,2,4-triazolin-5-one

Nefazodone, sold formerly under the brand names Serzone, Dutonin, and Nefadar among others, is an atypical antidepressant medication which is used in the treatment of depression and for other uses. Nefazodone was withdrawn in most countries by 2004 (due to liver toxicity). On December 2021, it was published that despite shortage it is still available in the United States.As of February 2026 it is available in the United States in generic form. The medication is taken by mouth.

Research

829 papers

Nefazodone.2012
Nefazodone: a new antidepressant.American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists · 1995
Nefazodone: its place among antidepressants.The Annals of pharmacotherapy · 1996
Clinical pharmacokinetics of nefazodone.Clinical pharmacokinetics · 1997
Nefazodone-induced mania.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 1995

via PubMed

Wikidata facts

Mass: 469.224

Show 5 more facts

chemical formula: C₂₅H₃₂ClN₅O₂
canonical SMILES: CCC1=NN(C(=O)N1CCOC2=CC=CC=C2)CCCN3CCN(CC3)C4=CC(=CC=C4)Cl
World Health Organisation international non-proprietary name: nefazodone
defined daily dose: 0.4
Commons category: Nefazodone

Sources (6)

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