Structure via PubChem · Public domain (PubChem)
nefazodon
Sign in to saveAlso known as BMY-13754, MJ-13754-1, 1-{3-[4-(m-chlorophenyl)-1-piperazinyl]propyl}-3-ethyl-4-(2-phenoxyethyl)-delta2-1,2,4-triazolin-5-one
kimyasal bileşik
Chemical data
- Formula
- C25H32ClN5O2
- Molecular weight
- 470 g/mol
- IUPAC name
- 2-[3-[4-(3-chlorophenyl)piperazin-1-yl]propyl]-5-ethyl-4-(2-phenoxyethyl)-1,2,4-triazol-3-one
- SMILES
- CCC1=NN(C(=O)N1CCOC2=CC=CC=C2)CCCN3CCN(CC3)C4=CC(=CC=C4)Cl
- InChIKey
- VRBKIVRKKCLPHA-UHFFFAOYSA-N
- XLogP
- 4.3
- Polar surface area
- 51.6 Ų
- H-bond donors
- 0
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
Withdrawn- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1994
- Admin. routes
- oral
- Indications
- cocaine dependence, cannabis dependence, major depressive disorder
via ChEMBL · EBI
Research
829 papers- Nefazodone.2012
- Nefazodone: a new antidepressant.American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists · 1995
- Nefazodone: its place among antidepressants.The Annals of pharmacotherapy · 1996
- Clinical pharmacokinetics of nefazodone.Clinical pharmacokinetics · 1997
- Nefazodone-induced mania.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 1995
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 469.224
- Has use
- medication
Show 8 more facts
- chemical formula
- C₂₅H₃₂ClN₅O₂
- significant drug interaction
- tranylcypromine
- medical condition treated
- depression
- canonical SMILES
- CCC1=NN(C(=O)N1CCOC2=CC=CC=C2)CCCN3CCN(CC3)C4=CC(=CC=C4)Cl
- World Health Organisation international non-proprietary name
- nefazodone
- defined daily dose
- 0.4
- Commons category
- Nefazodone
- physically interacts with
- solute carrier family 6 member 4
Sources (6)
via Wikidata · CC0