Structure via PubChem · Public domain (PubChem)
نیمسولید
Sign in to saveAlso known as R-805, Nimesulide
Nimesulide is a nonsteroidal anti-inflammatory drug (NSAID) with pain medication and fever reducing properties. Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis, and primary dysmenorrhoea in adolescents and adults above 12 years old.
Chemical data
- Formula
- C13H12N2O5S
- Molecular weight
- 308.31 g/mol
- IUPAC name
- N-(4-nitro-2-phenoxyphenyl)methanesulfonamide
- SMILES
- CS(=O)(=O)NC1=C(C=C(C=C1)[N+](=O)[O-])OC2=CC=CC=C2
- InChIKey
- HYWYRSMBCFDLJT-UHFFFAOYSA-N
- XLogP
- 2.6
- Polar surface area
- 110 Ų
- H-bond donors
- 1
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
Withdrawn- Max clinical phase
- Approved
- Molecule type
- Small molecule
- Indications
- rheumatic disease, Arthralgia, Myalgia, pain
via ChEMBL · EBI
Research
1,915 papersvia PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 308.047
- Has use
- medication
Show 6 more facts
- Commons category
- Nimesulide
- chemical formula
- C₁₃H₁₂N₂O₅S
- canonical SMILES
- CS(=O)(=O)NC1=C(C=C(C=C1)[N+](=O)[O-])OC2=CC=CC=C2
- defined daily dose
- 0.2
- MCN code
- 2935.90.94
- physically interacts with
- Prostaglandin-endoperoxide synthase 2
Sources (6)
via Wikidata · CC0