Structure via PubChem · Public domain (PubChem)
nylidrin
Sign in to saveAlso known as Buphenine, Buphenin, Bupheninum, Bufenina
Buphenine, also known as nylidrin and sold under the brand name Arlidin, is a β2 adrenoreceptor agonist that acts as a vasodilator.
Chemical data
- Formula
- C19H25NO2
- Molecular weight
- 299.4 g/mol
- IUPAC name
- 4-[1-hydroxy-2-(4-phenylbutan-2-ylamino)propyl]phenol
- SMILES
- CC(CCC1=CC=CC=C1)NC(C)C(C2=CC=C(C=C2)O)O
- InChIKey
- PTGXAUBQBSGPKF-UHFFFAOYSA-N
- XLogP
- 3.5
- Polar surface area
- 52.5 Ų
- H-bond donors
- 3
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- cardiovascular disease
via ChEMBL · EBI
Research
194 papers- In Vitro and In Vivo Antiviral Activity of Nylidrin by Targeting the Hemagglutinin 2-Mediated Membrane Fusion of Influenza A Virus.Viruses · 2020
- Effects of isoxuprine and nylidrin on adrenoreceptors in rat vas deferens.Journal of autonomic pharmacology · 1985
- Nylidrin (Arlidin) poisoning.Pediatrics · 1974
- Nylidrin: a potent anti-hypertensive agent in hypertensive rats.Research communications in chemical pathology and pharmacology · 1979
- A randomized double-dummy comparison between indomethacin and nylidrin in threatened preterm labor.Obstetrics and gynecology · 1991
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 299.189
Show 4 more facts
- chemical formula
- C₁₉H₂₅NO₂
- canonical SMILES
- CC(CCC1=CC=CC=C1)NC(C)C(C2=CC=C(C=C2)O)O
- Commons category
- Buphenine
- defined daily dose
- 30
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
{{Drugbox | image = Buphenine.svg | image_class = skin-invert-image | width =
| tradename = Arlidin | Drugs.com = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration =
Excerpted from Wikipedia’s “nylidrin” article, available under the CC BY-SA 4.0 licence.
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via Wikidata sitelinks · CC0