Structure via PubChem · Public domain (PubChem)
ornipressin
Sign in to saveOrnipressin is a vasoconstrictor, haemostatic and renal agent.
In the Vinony graph
Vinony's link graph records 68 inbound references to ornipressin, and connects out to arginine vasopressin, lithium and kidney.
It sits within the topics Antidiuretics, ECHA InfoCard ID from Wikidata and Nonapeptides.
Vinony links it to 10 Wikipedia language editions.
Chemical data
- Formula
- C45H63N13O12S2
- Molecular weight
- 1042.2 g/mol
- IUPAC name
- (2S)-N-[(2S)-5-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxopentan-2-yl]-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide
- SMILES
- C1C[C@H](N(C1)C(=O)[C@@H]2CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N2)CC(=O)N)CCC(=O)N)CC3=CC=CC=C3)CC4=CC=C(C=C4)O)N)C(=O)N[C@@H](CCCN)C(=O)NCC(=O)N
- InChIKey
- MUNMIGOEDGHVLE-LGYYRGKSSA-N
- XLogP
- -4.2
- Polar surface area
- 476 Ų
- H-bond donors
- 13
- H-bond acceptors
- 16
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Protein
via ChEMBL · EBI
Research
187 papers- The pharmacology of ornipressin (POR-8): a local vasoconstrictor used in surgery.European journal of anaesthesiology · 1998
- Hemodynamic effects of endobronchial application of ornipressin versus terlipressin.Respiration; international review of thoracic diseases · 2004
- Ornipressin in the treatment of functional renal failure in decompensated liver cirrhosis. Effects on renal hemodynamics and atrial natriuretic factor.Gastroenterology · 1991
- Ornipressin (Por 8): An efficient alternative to counteract hypotension during combined general/epidural anesthesia.Anesthesia and analgesia · 2000
- Hepatorenal failure.Clinics in liver disease · 2000
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 1041.416
Show 3 more facts
- chemical formula
- C₄₅H₆₃N₁₃O₁₂S₂
- canonical SMILES
- C1CC(N(C1)C(=O)C2CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N2)CC(=O)N)CCC(=O)N)CC3=CC=CC=C3)CC4=CC=C(C=C4)O)N)C(=O)NC(CCCN)C(=O)NCC(=O)N
- isomeric SMILES
- C1C[C@H](N(C1)C(=O)[C@@H]2CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N2)CC(=O)N)CCC(=O)N)CC3=CC=CC=C3)CC4=CC=C(C=C4)O)N)C(=O)N[C@@H](CCCN)C(=O)NCC(=O)N
Sources (1)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Ornipressin is a vasoconstrictor, haemostatic and renal agent.
==References==
Excerpted from Wikipedia’s “ornipressin” article, available under the CC BY-SA 4.0 licence.
Available in 10 languages
via Wikidata sitelinks · CC0
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