Structure via PubChem · Public domain (PubChem)
pantetheine
Sign in to saveAlso known as (R)-Pantetheine, Lactobacillus bulgaricus factor, D-Pantetheine
Pantetheine is the cysteamine amide analog of pantothenic acid (vitamin B5). The dimer of this compound, pantethine is more commonly known, and is considered to be the most potent form of vitamin B5. Pantetheine is an intermediate in the catabolism of coenzyme A by the body.
Chemical data
- Formula
- C11H22N2O4S
- Molecular weight
- 278.37 g/mol
- IUPAC name
- (2R)-2,4-dihydroxy-3,3-dimethyl-N-[3-oxo-3-(2-sulfanylethylamino)propyl]butanamide
- SMILES
- CC(C)(CO)[C@H](C(=O)NCCC(=O)NCCS)O
- InChIKey
- ZNXZGRMVNNHPCA-VIFPVBQESA-N
- XLogP
- -1
- Polar surface area
- 99.7 Ų
- H-bond donors
- 5
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
752 papers- Prebiotically plausible chemoselective pantetheine synthesis in water.Science (New York, N.Y.) · 2024
- Development of a Pantetheine Force Field Library for Molecular Modeling.Journal of chemical information and modeling · 2021
- Enzymatic hydrolysis of pantetheine.Methods in enzymology · 1986
- Toxicity of pantetheine.Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) · 1957
- Pantethine.Alternative medicine review : a journal of clinical therapeutic · 1998
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 278.13
Show 6 more facts
- isomeric SMILES
- CC(C)(CO)[C@H](C(=O)NCCC(=O)NCCS)O
- canonical SMILES
- CC(C)(CO)C(C(=O)NCCC(=O)NCCS)O
- chemical formula
- C₁₁H₂₂N₂O₄S
- found in taxon
- Caenorhabditis elegans
- Commons category
- Pantetheine
- subject has role
- primary metabolite
via Wikidata · CC0
~2 min read
Encyclopedic overview
3 sectionsContents
- Metabolism
- Prebiotic evolution
- References
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Pantetheine is the cysteamine amide analog of pantothenic acid (vitamin B5). The dimer of this compound, pantethine is more commonly known, and is considered to be the most potent form of vitamin B5. Pantetheine is an intermediate in the catabolism of coenzyme A by the body.
Excerpted from Wikipedia’s “pantetheine” article, available under the CC BY-SA 4.0 licence.