Structure via PubChem · Public domain (PubChem)
tasosartan
Sign in to saveAlso known as ANA-756, WAY-ana-756, WAY-ANA-756
Tasosartan is an angiotensin II receptor antagonist.
Chemical data
- Formula
- C23H21N7O
- Molecular weight
- 411.5 g/mol
- IUPAC name
- 2,4-dimethyl-8-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]-5,6-dihydropyrido[2,3-d]pyrimidin-7-one
- SMILES
- CC1=C2CCC(=O)N(C2=NC(=N1)C)CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5
- InChIKey
- ADXGNEYLLLSOAR-UHFFFAOYSA-N
- XLogP
- 3
- Polar surface area
- 101 Ų
- H-bond donors
- 1
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- cardiovascular disease
via ChEMBL · EBI
Research
19 papers- Tasosartan, enoltasosartan, and angiotensin II receptor blockade: the confounding role of protein binding.The Journal of pharmacology and experimental therapeutics · 2000
- Pharmacology of AT1-receptor blockers.Blood pressure. Supplement · 2001
- Novel human metabolites of the angiotensin-II antagonist tasosartan and their pharmacological effects.Bioorganic & medicinal chemistry letters · 2002
- High-throughput virtual screening of drug databanks for potential inhibitors of SARS-CoV-2 spike glycoprotein.Journal of biomolecular structure & dynamics · 2022
- Angiotensin II-receptor antagonists: an overview.American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists · 2000
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 411.180758
- Has use
- medication
Show 5 more facts
- Commons category
- Tasosartan
- chemical formula
- C₂₃H₂₁N₇O
- World Health Organisation international non-proprietary name
- tasosartan
- canonical SMILES
- CC1=C2CCC(=O)N(C2=NC(=N1)C)CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5
- subject has role
- angiotensin II receptor antagonist
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
{{Drugbox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 444132346 | IUPAC_name = 2,4-dimethyl-8-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-5,8-dihydropyrido[2,3-d]pyrimidin-7(6H)-one | image = Tasosartan.svg | image_class = skin-invert-image
| tradename = | pregnancy_category = N/A | legal_status = Withdrawn | routes_of_administration =
Excerpted from Wikipedia’s “tasosartan” article, available under the CC BY-SA 4.0 licence.