Structure via PubChem · Public domain (PubChem)
pimethixene
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Pimethixene is an antihistamine and anticholinergic of the thioxanthene chemical class originally developed to treat hyperactivity, anxiety, sleep disorders, and allergy. It is also used for anesthesia and as a bronchodilator (to dilate the bronchi and bronchioles for more airflow).
Chemical data
- Formula
- C19H19NS
- Molecular weight
- 293.4 g/mol
- IUPAC name
- 1-methyl-4-thioxanthen-9-ylidenepiperidine
- SMILES
- CN1CCC(=C2C3=CC=CC=C3SC4=CC=CC=C42)CC1
- InChIKey
- NZLVRVYNQYGMAB-UHFFFAOYSA-N
- XLogP
- 3.9
- Polar surface area
- 28.5 Ų
- H-bond donors
- 0
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- allergic disease
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 293.124
Show 3 more facts
- chemical formula
- C₁₉H₁₉NS
- canonical SMILES
- CN1CCC(=C2C3=CC=CC=C3SC4=CC=CC=C42)CC1
- World Health Organisation international non-proprietary name
- pimethixene
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
Pimethixene is an antihistamine and anticholinergic of the thioxanthene chemical class originally developed to treat hyperactivity, anxiety, sleep disorders, and allergy. It is also used for anesthesia and as a bronchodilator (to dilate the bronchi and bronchioles for more airflow).
In combination with pholcodine, it was sold in France by Laboratoires Salvoxyl in the 1970s as the antitussive Salvodex. Pimethixene alone is still available in Brazil under the trade name Muricalm.
Excerpted from Wikipedia’s “pimethixene” article, available under the CC BY-SA 4.0 licence.