pipofezine
Sign in to savePipofezine, sold under the brand name Azafen or Azaphen, is a tricyclic antidepressant approved in Russia for the treatment of depression. It was introduced in the late 1960s and is still used today.
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 297.159
Show 4 more facts
- chemical formula
- C₁₆H₁₉N₅O
- canonical SMILES
- CN1CCN(CC1)C2=NN=C3C(=C2)N(C4=CC=CC=C4O3)C
- medical condition treated
- depression
- Commons category
- Pipofezine
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Encyclopedic overview
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Pipofezine, sold under the brand name Azafen or Azaphen, is a tricyclic antidepressant approved in Russia for the treatment of depression. It was introduced in the late 1960s and is still used today.
Pipofezine has been shown to act as a potent inhibitor of the reuptake of serotonin. In addition to its antidepressant action, pipofezine has sedative effects as well, suggesting antihistamine activity. Other properties such as anticholinergic or antiadrenergic actions are less clear but are likely.
Excerpted from Wikipedia’s “pipofezine” article, available under the CC BY-SA 4.0 licence.
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