protriptyline
Sign in to saveAlso known as MK-240, N-methyl-5H-dibenzo[a,d]cycloheptene-5-propylamine, 7-(3-methylaminopropyl)-1,2:5,6-dibenzocycloheptatriene, 5-(3-methylaminopropyl)-5H-dibenzo[a,d]cycloheptene, amimetilina, 3-(5H-dibenzo[a,d]cyclohepten-5-yl)-N-methyl-1-propanamine, N-methyl-5H-dibenzo[a,d]cycloheptene-5-propanamine
chemische verbinding
Key facts
- Drug.ChEMBL
- 668
- Drug.excretion
- Urine: 50%Feces: minor
- Drug.verifiedrevid
- 464375600
- Drug.IUPAC_name
- 3-(5H-dibenzo[a,d][7]annulen-5-yl)-N-methylpropan-1-amine
- Drug.image
- Protriptyline.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 200px
- Drug.caption
- Above: molecular structure of protriptyline Below: 3D representation of a protriptyline molecule
- Drug.image2
- Protripyline 3D.png
- Drug.image_class2
- bg-transparent
- Drug.tradename
- Vivactyl, others
- Drug.MedlinePlus
- a604025
- Drug.pregnancy_US
- C
- Drug.legal_BR
- C1
- Drug.legal_status
- Rx-only
- Drug.routes_of_administration
- Oral
- Drug.bioavailability
- 77–93%
- Drug.protein_bound
- 92%
via Wikipedia infobox
Research
420 papers- Protriptyline.2006
- Protriptyline.2012
- Protriptyline.2026
- Protriptyline kinetics.Clinical pharmacology and therapeutics · 1978
- Protriptyline, a tricyclic antidepressant, inhibits voltage-dependent K+ channels in rabbit coronary arterial smooth muscle cells.Acta biochimica et biophysica Sinica · 2020
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 263.1674
- Has use
- medication
Show 8 more facts
- chemical formula
- C₁₉H₂₁N
- significant drug interaction
- tranylcypromine
- World Health Organisation international non-proprietary name
- protriptyline
- canonical SMILES
- CNCCCC1C2=CC=CC=C2C=CC3=CC=CC=C13
- subject has role
- tricyclic antidepressant
- defined daily dose
- 30
- physically interacts with
- solute carrier family 6 member 4
- Commons category
- Protriptyline
Sources (3)
via Wikidata · CC0