Structure via PubChem · Public domain (PubChem)
Rizatriptan
Sign in to saveAlso known as MK-0462, MK-462, MK-A462, N,N-dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]-ethanamine, risatriptan, N,N-dimethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indole-3-ethanamine, MK 462 free base
Arzneistoff
Chemical data
- Formula
- C15H19N5
- Molecular weight
- 269.34 g/mol
- IUPAC name
- N,N-dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethanamine
- SMILES
- CN(C)CCC1=CNC2=C1C=C(C=C2)CN3C=NC=N3
- InChIKey
- ULFRLSNUDGIQQP-UHFFFAOYSA-N
- XLogP
- 1.7
- Polar surface area
- 49.7 Ų
- H-bond donors
- 1
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1998
- Admin. routes
- oral
- Indications
- migraine disorder, migraine with aura, migraine without aura
via ChEMBL · EBI
Research
574 papers- Rizatriptan.2006
- Rizatriptan as an Over-the-Counter Triptan in the Treatment of Migraine Attacks.Pain and therapy · 2024
- [Rizatriptan].Neurologia (Barcelona, Spain) · 2000
- Rizatriptan vs Placebo for Attacks of Vestibular Migraine: A Randomized Clinical Trial.JAMA neurology · 2025
- Rizatriptan in migraine.Expert review of neurotherapeutics · 2005
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 269.164046
- Has use
- medication
Show 8 more facts
- significant drug interaction
- phenelzine
- chemical formula
- C₁₅H₁₉N₅
- canonical SMILES
- CN(C)CCC1=CNC2=C1C=C(C=C2)CN3C=NC=N3
- World Health Organisation international non-proprietary name
- rizatriptan
- defined daily dose
- 10
- subject has role
- serotonin receptor agonists
- medical condition treated
- migraine
- Commons category
- Rizatriptan
via Wikidata · CC0
Article · Deutsch
Rizatriptan ist ein selektiver Serotoninagonist aus der Gruppe der Triptane und ist als Arzneistoff zur Behandlung von Migränekopfschmerzen zugelassen. Die Zulassung erfolgte 1998 in den USA durch die FDA und im selben Jahr auch in Deutschland durch das Bundesinstitut für Arzneimittel und Medizinprodukte. Rizatriptan ist verschreibungspflichtig.
Abstract from DBpedia / Wikipedia · CC BY-SA