Structure via PubChem · Public domain (PubChem)
ریزاتریپتان
Sign in to saveAlso known as MK-0462, MK-462, MK-A462, N,N-dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]-ethanamine, risatriptan, N,N-dimethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indole-3-ethanamine, MK 462 free base
Rizatriptan, sold under the brand name Maxalt among others, is a medication used for the treatment of migraine headaches. It is taken by mouth. It can also be applied on the tongue. It is a serotonin (5-HT) 1B/1D receptor agonist (triptan).
Chemical data
- Formula
- C15H19N5
- Molecular weight
- 269.34 g/mol
- IUPAC name
- N,N-dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethanamine
- SMILES
- CN(C)CCC1=CNC2=C1C=C(C=C2)CN3C=NC=N3
- InChIKey
- ULFRLSNUDGIQQP-UHFFFAOYSA-N
- XLogP
- 1.7
- Polar surface area
- 49.7 Ų
- H-bond donors
- 1
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Research
574 papers- Rizatriptan.2006
- Rizatriptan as an Over-the-Counter Triptan in the Treatment of Migraine Attacks.Pain and therapy · 2024
- [Rizatriptan].Neurologia (Barcelona, Spain) · 2000
- Rizatriptan vs Placebo for Attacks of Vestibular Migraine: A Randomized Clinical Trial.JAMA neurology · 2025
- Rizatriptan in migraine.Expert review of neurotherapeutics · 2005
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 269.164046
- Has use
- medication
Show 8 more facts
- significant drug interaction
- phenelzine
- chemical formula
- C₁₅H₁₉N₅
- canonical SMILES
- CN(C)CCC1=CNC2=C1C=C(C=C2)CN3C=NC=N3
- World Health Organisation international non-proprietary name
- rizatriptan
- defined daily dose
- 10
- subject has role
- serotonin receptor agonists
- medical condition treated
- migraine
- Commons category
- Rizatriptan
via Wikidata · CC0