Structure via PubChem · Public domain (PubChem)
sarpogrelate
Sign in to saveAlso known as Anplag®, LS-187,118, MCI-9042
Sarpogrelate (, ), sold under the brand names Anplag and Sapodifil, is a serotonin 5-HT2 receptor antagonist which is used in the treatment of arterial occlusive disorders such as peripheral artery disease in Japan, South Korea, and China. Development in the United States and the European Union was discontinued and it is not available in these regions.
Chemical data
- Formula
- C24H31NO6
- Molecular weight
- 429.5 g/mol
- IUPAC name
- 4-[1-(dimethylamino)-3-[2-[2-(3-methoxyphenyl)ethyl]phenoxy]propan-2-yl]oxy-4-oxobutanoic acid
- SMILES
- CN(C)CC(COC1=CC=CC=C1CCC2=CC(=CC=C2)OC)OC(=O)CCC(=O)O
- InChIKey
- FFYNAVGJSYHHFO-UHFFFAOYSA-N
- XLogP
- 1.2
- Polar surface area
- 85.3 Ų
- H-bond donors
- 1
- H-bond acceptors
- 7
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 3
- Molecule type
- Small molecule
- Indications
- peripheral arterial disease, cerebral infarction
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 429.215
- Has use
- medication
Show 3 more facts
- chemical formula
- C₂₄H₃₁NO₆
- subject has role
- platelet aggregation inhibitors
- canonical SMILES
- CN(C)CC(COC1=CC=CC=C1CCC2=CC(=CC=C2)OC)OC(=O)CCC(=O)O
via Wikidata · CC0
~3 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
{{Drugbox | Verifiedfields = verified | verifiedrevid = 407721136 | image = Sarpogrelate structure.svg | image_class = skin-invert-image | width = 250px
| tradename = Anplag; Sapodifil | Drugs.com = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | routes_of_administration = | class = Serotonin 5-HT2 receptor antagonist; Serotonin 5-HT2A receptor antagonist; Anticoagulant; Platelet aggregation inhibitor | ATC_prefix = None | ATC_suffix =
Excerpted from Wikipedia’s “sarpogrelate” article, available under the CC BY-SA 4.0 licence.