ستوپرون

Setoperone (; ; developmental code name R-52245) is a compound that is a ligand to the 5-HT2A receptor. It can be radiolabeled with the radioisotope fluorine-18 and used as a radioligand with positron emission tomography (PET). Several research studies have used the radiolabeled setoperone in neuroimaging for the studying neuropsychiatric disorders, such as depression or schizophrenia. The drug was first described by at least 1984.

Chemical data

Formula: C21H24FN3O2S
Molecular weight: 401.5 g/mol
IUPAC name: 6-[2-[4-(4-fluorobenzoyl)piperidin-1-yl]ethyl]-7-methyl-2,3-dihydro-[1,3]thiazolo[3,2-a]pyrimidin-5-one
SMILES: CC1=C(C(=O)N2CCSC2=N1)CCN3CCC(CC3)C(=O)C4=CC=C(C=C4)F
InChIKey: RBGAHDDQSRBDOG-UHFFFAOYSA-N
XLogP: 2.8
Polar surface area: 78.3 Å²
H-bond donors: 0
H-bond acceptors: 6
Formal charge: 0

via PubChem

Drug data · ChEMBL

Max clinical phase: Phase 2
Molecule type: Small molecule

via ChEMBL · EBI

Wikidata facts

Subclass of: chemical compound
Mass: 401.157

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canonical SMILES: CC1=C(C(=O)N2CCSC2=N1)CCN3CCC(CC3)C(=O)C4=CC=C(C=C4)F
chemical formula: C₂₁H₂₄FN₃O₂S
subject has role: contrast agent
Commons category: Setoperone

Sources (2)

via Wikidata · CC0

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via Wikidata sitelinks · CC0