Setoperone (; ; developmental code name R-52245) is a compound that is a ligand to the 5-HT2A receptor. It can be radiolabeled with the radioisotope fluorine-18 and used as a radioligand with positron emission tomography (PET). Several research studies have used the radiolabeled setoperone in neuroimaging for the studying neuropsychiatric disorders, such as depression or schizophrenia. The drug was first described by at least 1984.
{{Infobox drug | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 449587261 | drug_name = | image = Setoperone.svg | image_class = skin-invert-image | width = | caption =
| pronounce = | tradename = | Drugs.com = | MedlinePlus = | licence_CA = | licence_EU = | DailyMedID = | licence_US = | pregnancy_AU = | pregnancy_category = | dependency_liability = | addiction_liability = | routes_of_administration = | class = Serotonin 5-HT2A receptor antagonist | ATC_prefix = None | ATC_suffix =
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).