Structure via PubChem · Public domain (PubChem)
setoperone
Sign in to saveSetoperone (; ; developmental code name R-52245) is a compound that is a ligand to the 5-HT2A receptor. It can be radiolabeled with the radioisotope fluorine-18 and used as a radioligand with positron emission tomography (PET). Several research studies have used the radiolabeled setoperone in neuroimaging for the studying neuropsychiatric disorders, such as depression or schizophrenia. The drug was first described by at least 1984.
Chemical data
- Formula
- C21H24FN3O2S
- Molecular weight
- 401.5 g/mol
- IUPAC name
- 6-[2-[4-(4-fluorobenzoyl)piperidin-1-yl]ethyl]-7-methyl-2,3-dihydro-[1,3]thiazolo[3,2-a]pyrimidin-5-one
- SMILES
- CC1=C(C(=O)N2CCSC2=N1)CCN3CCC(CC3)C(=O)C4=CC=C(C=C4)F
- InChIKey
- RBGAHDDQSRBDOG-UHFFFAOYSA-N
- XLogP
- 2.8
- Polar surface area
- 78.3 Ų
- H-bond donors
- 0
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 401.157
Show 4 more facts
- canonical SMILES
- CC1=C(C(=O)N2CCSC2=N1)CCN3CCC(CC3)C(=O)C4=CC=C(C=C4)F
- chemical formula
- C₂₁H₂₄FN₃O₂S
- subject has role
- contrast agent
- Commons category
- Setoperone
Sources (2)
via Wikidata · CC0
~3 min read
Encyclopedic overview
4 sectionsContents
- Chemistry
- Synthesis
- See also
- References
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| pronounce = | tradename = | Drugs.com = | MedlinePlus = | licence_CA = | licence_EU = | DailyMedID = | licence_US = | pregnancy_AU = | pregnancy_category = | dependency_liability = | addiction_liability = | routes_of_administration = | class = Serotonin 5-HT2A receptor antagonist | ATC_prefix = None | ATC_suffix =
Excerpted from Wikipedia’s “setoperone” article, available under the CC BY-SA 4.0 licence.