Structure via PubChem · Public domain (PubChem)
SKF-38393
Sign in to saveAlso known as R(+)SKF38393, SKF 38393, SKF-38,393, SKF38393
SKF-38393 is a synthetic compound of the 3-benzazepine family which acts as a selective dopamine D1 and D5 receptor partial agonist. It has stimulant and anorectic effects.
Chemical data
- Formula
- C16H17NO2
- Molecular weight
- 255.31 g/mol
- IUPAC name
- 5-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol
- SMILES
- C1CNCC(C2=CC(=C(C=C21)O)O)C3=CC=CC=C3
- InChIKey
- JUDKOGFHZYMDMF-UHFFFAOYSA-N
- XLogP
- 2.5
- Polar surface area
- 52.5 Ų
- H-bond donors
- 3
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 255.125929
Show 3 more facts
- chemical formula
- C₁₆H₁₇NO₂
- canonical SMILES
- C1CNCC(C2=CC(=C(C=C21)O)O)C3=CC=CC=C3
- subject has role
- dopamine agonist
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- See also
- References
- External links
SKF-38393 is a synthetic compound of the 3-benzazepine family which acts as a selective dopamine D1 and D5 receptor partial agonist. It has stimulant and anorectic effects.
The trimethylation of SKF-38,393 leads to a named agent called trepipam. As with fenoldopam, the inclusion of a chlorine halogen gave an agent that is called SKF-81,297.
Excerpted from Wikipedia’s “SKF-38393” article, available under the CC BY-SA 4.0 licence.