SKF89976A
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SKF-89976A is an anticonvulsant, acting as a GABA reuptake inhibitor via blockade of GAT-1. ==Synthesis== thumb|center|500px|Synthesis: Patent: Ex 1: Finkelstein Sn2 alkylation between 1,1-Diphenyl-4-bromobutene [6078-95-1] (1) & Ethyl nipecotate [5006-62-2] (2) gives [89203-62-3] (3). Optional saponification of the ester group gives the title amino-acid compound (4).
Wikidata facts
- Mass
- 335.188529
Show 4 more facts
- chemical formula
- C₂₂H₂₅NO₂
- isomeric SMILES
- OC(=O)C1CCCN(C1)CC/C=C(\C2=CC=CC=C2)/C3=CC=CC=C3
- canonical SMILES
- C1CC(CN(C1)CCC=C(C2=CC=CC=C2)C3=CC=CC=C3)C(=O)O
- Commons category
- SKF-89976A
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Article
4 sectionsContents
- Synthesis
- Related compounds
- References
- External links
SKF-89976A is an anticonvulsant, acting as a GABA reuptake inhibitor via blockade of GAT-1. ==Synthesis== thumb|center|500px|Synthesis: Patent: Ex 1: Finkelstein Sn2 alkylation between 1,1-Diphenyl-4-bromobutene [6078-95-1] (1) & Ethyl nipecotate [5006-62-2] (2) gives [89203-62-3] (3). Optional saponification of the ester group gives the title amino-acid compound (4).
==Related compounds== [[File:NNC-47-0011.svg|thumb|center|150px|NNC-47-0011: Patent:]]