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Org-25935
Sign in to saveORG-25935, also known as SCH-900435 is a synthetic drug developed by Organon International, which acts as a selective inhibitor of the glycine transporter GlyT-1. In animal tests it reduces alcohol consumption and has analgesic and anticonvulsant effects, but it has mainly been studied for its antipsychotic properties, and in human trials it was shown to effectively counteract the effects of the dissociative drug ketamine.
In the Vinony graph
Within Vinony's link graph, Org-25935 is referenced by 131 other articles, and connects out to ginkgolide, picrotoxin and zinc.
It is catalogued under topics including Alpha-Amino acids, Chemical articles with multiple CAS registry numbers and Chemical pages without DrugBank identifier.
Its subject is documented across 5 Wikipedia language editions.
Chemical data
- Formula
- C21H25NO3
- Molecular weight
- 339.4 g/mol
- IUPAC name
- 2-[[(1R,2S)-6-methoxy-1-phenyl-1,2,3,4-tetrahydronaphthalen-2-yl]methyl-methylamino]acetic acid
via PubChem
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 339.183
Show 4 more facts
- chemical formula
- C₂₁H₂₅NO₃
- canonical SMILES
- CN(CC1CCC2=C(C1C3=CC=CC=C3)C=CC(=C2)OC)CC(=O)O
- isomeric SMILES
- CN(C[C@H]1CCc2cc(ccc2[C@H]1c3ccccc3)OC)CC(=O)O
- Commons category
- Org 25935
Sources (2)
via Wikidata · CC0
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Encyclopedic overview
2 sectionsContents
- See also
- References
ORG-25935, also known as SCH-900435 is a synthetic drug developed by Organon International, which acts as a selective inhibitor of the glycine transporter GlyT-1. In animal tests it reduces alcohol consumption and has analgesic and anticonvulsant effects, but it has mainly been studied for its antipsychotic properties, and in human trials it was shown to effectively counteract the effects of the dissociative drug ketamine.
== See also == Glycine reuptake inhibitor
Excerpted from Wikipedia’s “Org-25935” article, available under the CC BY-SA 4.0 licence.