Also known as Ribonucleoproteins, Small Nuclear, small nuclear ribonucleoprotein
snRNPs (pronounced "snurps"), or small nuclear ribonucleoproteins, are RNA-protein complexes that combine with unmodified pre-mRNA and various other proteins to form a spliceosome, a large RNA-protein molecular complex upon which splicing of pre-mRNA occurs. The action of snRNPs is essential to the removal of introns from pre-mRNA, a critical aspect of post-transcriptional modification of RNA, occurring only in the nucleus of eukaryotic cells. Additionally, U7 snRNP is not involved in splicing at all, as U7 snRNP is responsible for processing the 3′ stem-loop of histone pre-mRNA.
via PubMed
snRNP (od ang. small nuclear ribonucleoproteins = małe jądrowe nukleoproteiny) – zbudowane z białek i snRNA cząstki biorące udział w splicingu. Komponent snRNA zapewnia specyficzność kompleksu w stosunku do intronów, "rozpoznając" sekwencje zawierające sygnały splicingu na końcu 5' i końcu 3' oraz w tzw. miejscu rozgałęzienia. W połączeniu z białkami tworzą spliceosomy. snRNP zostały odkryte przez Michaela R. Lernera i Joan A. Steitz.
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Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).